The Loud House/Despicable Me

Lincoln Loud as Gru

Clyde as Dru

Ronnie-Anne as Lucy

Penny (from Mr. Peabody & Sherman) as Agnes

Vanellope von Schweetz (from Wreck-It Ralph) as Edith

Leni Loud as Margo

Gobber (from How to Train Your Dragon) as Dr. Neferio

Chandler as Vector

Drago Bludvist (from How to Train Your Dragon 2) as El Macho

Grimmel the Grisly (from How to Train Your Dragon: The Hidden World) as Balthazar Bratt